The city's earliest botanical garden dated to 1688 as a small medicinal plant collection outside the city walls, near today's Rue Paré. It subsequently fell into disuse but in 1726 was revived as a Royal Garden for exotic plants. By 1790 the garden contained more than 600 species but by 1795 the garden had dwindled to fewer than 150 exotic plants; it again reverted to a medicinal garden, and slowly declined until its demise in 1877.

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