The Catacombs of Domitilla is a complex of catacombs on the Via Ardeatina in Rome. The oldest graves date from the 1st and 2nd century AD. and even in late antiquity people were buried here. The best-known people who were buried here were the martyrs Nereus and Achilleus. The catacomb itself is named after Domittila Flavia, a noble woman from the gens Flavia, who converted to Christianity and died as a martyr.

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